Open Trials

Ovary

AGO-OVAR 26 / MATAO

MAintenance Therapy with Aromatase inhibitor in epithelial Ovarian cancer: a randomized double-blinded placebo-controlled multi-center phase III Trial (ENGOT-ov54/Swiss-GO-2/MATAO) including LOGOS (Low Grade Ovarian cancer Sub-study)

 

AGO-OVAR 27 / WoO

Window-of-opportunity proof-of-concept, non-randomized, open-label, phase II trial of Olaparib given alone (cohort A) or in combination with Durvalumab (cohort B) prior to primary debulking surgery in histologically proven high-grade epithelial ovarian cancer (EOC)

 

AGO-OVAR 28

Niraparib vs Niraparib in combination with Bevacizumab in patients with carboplatinum-taxane based chemotherapy in advanced ovarian cancer (A multicentre randomised phase III trial)

 

AGO-OVAR 2.41 / TEDOVA

Randomized Phase II study comparing neo-epitope based vaccine OSE2101 (TEDOPI®) with or without anti-PD1 (Pembrolizumab) versus best supportive care as maintenance treatment in platinum-sensitive recurrent ovarian cancer patient with controlled disease after Platinum-based chemotherapy

Endometrium / Vulva / Cervix

Surgical and translational issues

AGO-OVAR OP.6 ECLAT

Pelvic and para-aortic lymphadenectomy in patients with stage I or II endometrial cancer at high risk of recurrence. A multicenter, prospective randomized controlled trial.